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Wall Street Grill Opening In Fall

Greetings! Win Dinner for 2 by giving Tzedaka We have some big restaurant news to share but we have something even bigger to tell you about in which we need your help. As we alluded to back in April on Facebook, New York's newest kosher dining experience will be opening its doors on 75 Wall Street in early fall 2015. Wall Street Grill, a premiere upscale hangout, will feature indoor seating for 120 and a beautiful outdoor rooftop area seating 80. Private dining rooms will also be available for exclusive engagements. Click here to like them on Facebook. HOW TO GET IN FOR VIP OPENING WEEK? - DONATE TODAY! Wall Street Grill is offering a chance to win one of 5 "friends & family" complimentary Dinner for 2 packages during their opening week. They have partnered with the charity organization Shuvu.org and with charidy.com for a 24 hour only fund drive (started 11am today). In an attempt to raise an unprecedented $1.6 Million over the next 24 hours, every dollar you donate to Shuvu.org will be quadrupled by a group of generous matchers. Your donation of $25 will raise $100 for this great cause. If the full $1.6 Million isn't raised, all donations will be returned, it's all or nothing. So far, $720,000 has been raised! Spread the word & help Shuvu make a difference in the lives of children all over Israel. To be entered into the drawing for a complimentary "Dinner for 2" during opening week, donors of $18 or more should forward their donation email to friends@wallstreetgrill.com. Your email address will be used to keep you updated on their progress. The link to donate is: www.charidy.com/shuvu Tizku Lemitzvot and Thank you!

Israeli Researcher Makes Key Breakthrough In Combating Antibiotic Resistanc

By NoCamels Team June 09, 2015 0 Comments At its annual assembly in Geneva last week, the World Health Organization approved a radical and far-reaching plan to slow the rapid, extensive spread of antibiotic resistance around the world. The plan hopes to curb the rise caused by an unchecked use of antibiotics and lack of new antibiotics on the market. Now Tel Aviv University research published in PNAS introduces a promising new tool: a two-pronged system to combat this dangerous situation. The system wipes out antibiotic resistance in selected bacteria, and renders other bacteria more sensitive to antibiotics. The research, led by Prof. Udi Qimron is based on bacterial viruses called “phages”, which transfer “edited” DNA into resistant bacteria to kill off resistant strains and make others more sensitive to antibiotics. According to the researchers, the system, if ultimately applied to pathogens on hospital surfaces or medical personnel’s hands, could turn the tide on untreatable, often lethal bacterial infections. “Since there are only a few pathogens in hospitals that cause most of the antibiotic-resistance infections, we wish to specifically design appropriate sensitization treatments for each one of them,” Prof. Qimron says. “We will have to choose suitable combinations of DNA-delivering phages that would deliver the DNA into pathogens, and the suitable combination of ‘killing’ phages that could select the re-sensitized pathogens.” “Antibiotic-resistant pathogens constitute an increasing threat because antibiotics are designed to select resistant pathogens over sensitive ones,” Prof. Qimron says. “The injected DNA does two things: It eliminates the genes that cause resistance to antibiotics, and it confers protection against lethal phages. “We managed to devise a way to restore antibiotic sensitivity to drug-resistant bacteria, and also prevent the transfer of genes that create that resistance among bacteria,” he continues. Earlier research by Prof. Qimron revealed that bacteria could be sensitized to certain antibiotics — and that specific chemical agents could “choose” those bacteria more susceptible to antibiotics. His strategy harnesses the CRISPR-Cas system — a bacterial DNA-reprogramming system Prof. Qimron pioneered — as a tool to expand on established principles. According to the researchers, “selective pressure” exerted by antibiotics renders most bacteria resistant to them — hence the epidemic of lethal resistant infections in hospitals. No counter-selection pressure for sensitization of antibiotics is currently available. Prof. Qimron’s strategy actually combats this pressure — selecting for the population of pathogens exhibiting antibiotic sensitivity. “We believe that this strategy, in addition to disinfection, could significantly render infections once again treatable by antibiotics,” said Prof. Qimron. Prof. Qimron and his team are now poised to apply the CRISPR/phage system onpseudomonas aeruginosa — one of the world’s most prevalent antibiotic-resistant pathogens involved in hospital-acquired infections — and to test whether bacterial sensitization works in a more complex microbial environment: the mouse cage. Prof. Qimron is a member of the Department of Clinical Microbiology and Immunology at TAU’s Sackler Faculty of Medicine.

Researchers at Israel's Weitzman Institute First

To Grow Immune System Cells In Lab by ISRAEL21c | 05.21.15 5:55 pm The global science community is looking to Rehovot, where a team of Israeli scientists at the Weizmann Institute managed to grow lymphatic cells in the lab for the first time ever. For over a century, scientists have debated the origins of the lymphatic system—a parallel system to the blood vessels that serves as a conduit for everything from immune cells to fat molecules to cancer cells. This issue has now been resolved by Dr. Karina Yaniv of the Weizmann Institute’s Biological Regulation Department. In a study reported in Nature, Yaniv and her team revealed how the lymphatic system develops in the embryo. In the initial stages of the research project, Yaniv’s team members Julian Nicenboim and Dr. Guy Malkinson obtained images of developing zebrafish embryos, whose transparent bodies make it possible to document embryonic development in real time over several days. The scientists then played the movies backward, to identify the point at which the lymphatic system began to form. To their surprise, they discovered that the cells that give rise to lymphatic vessels always originated in the same part of the embryo’s major vein. In that spot, the scientists found a niche of angioblasts, the same cells that a hundred years earlier were thought to be the source of lymph vessels, but were later neglected by researchers. An in-depth genetic analysis, performed with the participation of graduate students Tal Lupo and Lihee Asaf, pointed to a gene called WNT5B, which was revealed to be the factor prompting stem cells to differentiate into lymphatic cells. When postdoctoral fellow Dr. Yogev Sela added WNT5B to human embryonic stem cells, these cells indeed differentiated into lymphatic cells—the first time such cells had been grown in the lab. “We started out by imaging zebrafish, and ended up finding a factor that makes it possible to create lymphatic cells,” said Yaniv. “That’s the beauty of research in developmental biology: The embryo holds the answers, and all we have to do is watch and learn.” The new research not only answers a longstanding question of how the lymph system arises, but can also provide important insights into disease, from metastasis to the abnormal accumulation of lymph fluids, particularly in the wake of surgery to remove cancerous tumors. The research was performed in collaboration with the laboratories of Prof. Itai Yanai from the Technion—Israel Institute of Technology, Dr. Jacob Hanna of Weizmann’s Molecular Genetics Department, and Prof. Nathan Lawson of the University of Massachusetts.


The BDS supporters do not hesitate to make use of the medical discoveries and services of Israeli and other Jewish doctors and institutions. Following is a very abbreviated list: Blood group identification for blood transfusion, Smallpox eradication, Penicillin, Diphtheria & Tetanus Antitoxin, Hepatitis-B Vaccine, Mammograms, Polio Vaccine, Polio vaccine, Aspirin, Warfarin (prevention of heart attacks & strokes), Cancer chemotherapy, Breaking the genetic code, Nuclear magnetic resonance, Flexible endoscope, Streptomycin (Tuberculosis), Cancer chemotherapy, Lasik eye surgery, Cardiac defibrillator, Controlled chlorination of drinking water supplies, Medical treatment at Israeli hospitals: Over 1500 wounded Syrians, Treated daughter of a high Hamas leader, Treated niece of Ayatollah Khomeini for reproductive issues and many more. It has been estimated that, depending on the assumptions used, the number of lives saved by Israeli and other Jewish discoveries has been 2.8-4.3 BILLION!! For more information, see www.jinfo.org/Life_Savers.html.

Israel’s Exelon inventor sees an end to Alzheimer’s

BY DAVID SHAMAH April 22, 2015, 5:08 pm 9 Dr. Marta Weinstock-Rosin, inventor of Exelon, a drug that improves memory and slows its decline in subjects with Alzheimer’s disease, is a big believer in the ability of medical science to help people live longer and better-quality lives. Alzheimer’s is a modern phenomenon; 100 years ago you never saw people like that, because they all died of other diseases before the brain degenerated.”And eventually, she believes, a preventive treatment will be found for Alzheimer’s and the other maladies of the brain, along with cancer, heart disease, and the other great medical challenges of the modern era. Exelon, the drug she created to treat Alzheimer’s, is just the beginning. “A young person today may live to see a time when Alzheimer’s and many of the other great challenges are preventable,” she said.Rivastigmine, commercially known as Exelon, is one of the most important drugs to have emerged from Israeli medical research labs in recent years. In recognition of this fact, its chief developer, Weinstock-Rosin, was awarded the Israel Prize for Medicine last year for her work. In many ways, Exelon, and its inventor, paved new paths in Israeli medicine, and Israeli society. Weinstock-Rosin, who is Orthodox, was born in Vienna and fled with her family to Britain in 1939, narrowly escaping from the Nazis. She came to Israel with her family in 1969, and became a professor at Hebrew University in 1981. In 1983, she became head of the Pharmacology department at the Hebrew University (now part of the Institute for Drug Research) in the Faculty of Medicine.Weinstock-Rosin’s drug Rivastigmine was incorporated by Novartis into the Exelon Patch, the first and only FDA-approved skin patch for treatment of Alzheimer’s disease, in which many researchers believe the cognitive decline results from a loss a brain neural transmitter called acetylcholine. Acetylcholine is necessary for communication between nerve cells. Rivastigmine prevents the breakdown of acetylcholine by an enzyme called acetylcholinesterase. Weinstock-Rosin’s research showed that by so doing it can slow the progress of memory loss in Alzheimer’s disease.As there currently is no cure for Alzheimer’s, Exelon is considered one of the more effective treatments for the disease. Used by patients either twice a day in capsules or once a day in patch form, Novartis sold more than $1 billion worth of Exelon in 2013.Novartis acquired Exelon from the Hebrew University’s technology transfer company, Yissum, which since 1964 has established numerous companies based on research done by Hebrew U scientists, including road safety innovator Mobileye. Altogether, products based on Hebrew University technologies that have been commercialized by Yissum generate $2 billion in annual sales. Weinstock-Rosin’s current research involves a drug called Ladostigil, originally developed together with Prof. Moussa Youdim of the Technion and Teva pharmaceuticals to treat Alzheimers like rivastigmine. Weinstock-Rosin discovered that at a much lower dose it can prevent the deterioration of memory in aging rats by a different mechanism of action and may also be able to do this in mild cognitive impairment (MCI), an early stages of Alzheimer’s disease in humans. The drug is now undergoing a three-year Phase II clinical trial in Israel and Europe in subjects with MCI for the prevention of Alzheimer’s disease.For doctors, researching diseases of the brain is the next great challenge, said Weinstock-Rosin. “We have done a great deal to keep people alive longer, but now we have to help them live better-quality lives by discovering ways to slow down or even prevent mental deterioration. What good will it be to live to be 150 but without mental faculties?”

Israeli-American Team Unveils Revolutionary Drug in Fight Against Skin Canc

Team member Jacob Schachter of Sheba Medical Center believes the new treatment 'will turn melanoma into a treatable chronic disease.' Nechama Duek Published: 06.08.14, 16:32 / Israel Culture A groundbreaking biological treatment for cancer jointly developed by Israeli and American researchers has been presented at an international conference on cancer research in Chicago. "This medicine is a miracle cure - it's a real breakthrough," says Prof. Jacob Schachter, head of research and treatment of melanoma and skin cancer at Sheba Medical Center, who is part of the international research team for the medicine. The new treatment comes from the field of immunotherapy, which helps the immune system fight cancer, unlike chemotherapy, which attacks the tumor itself. There are various types of cancerous tumors, such as melanoma, that use a "shield" to protect themselves from being identified by the immune system. The new medicine paralyzes this type of screening mechanism, so the immune system can recognize the cancer and attack it. The results of the international research suggest that using the medicine Pembrolizumab, also known as MK-3475, yields impressive survival rates in patients with advanced cancer, with 69 percent surviving one year and 63 percent surviving 18 months. Without this treatment, patients with metastatic melanoma die from the disease within 4-5 months, after reaching stage four cancer. The research tested 41,818 patients, 1,800 of them in Israel. The research took place over a decade, while the clinical stage took four years. The new medicine, which belongs to a new generation of biological drugs, yielded extraordinary results to the point that the FDA approved it for "compassionate use" (the use of an investigational drug outside a clinical trial by patients with life-threatening conditions) and it will be given for free to terminally ill patients. It is also be fast tracked for approval, which is expected by October. "One of my patients who suffered metastatic melanoma in very critical condition entered the trial, and within six weeks his body was completely clean of cancer," said Schachter. He stressed that because of the biological nature of the drug; its side effects are minimal and allows patients optimal quality of life. Merck, the American company that developed the drug, has a department in Israel called MSD, which operates a research division working in tandem with medical centers in Israel."We are on our way to turn melanoma a treatable chronic disease," said Schachter. "We are also seeing positive results in other types of cancer such as the urinary bladder, head neck and lungs". Prof. Alise Reicin, who heads the American team that developed the drug, termed it "definitely a breakthrough in the war against cancer". Thousands of doctors and researchers from around the world attended the conference of the American Society for Clinical Oncology, an annual event focusing on the latest medicine and research in cancer treatment. A significant number of this year's lectures were dedicated to research in biological medicine and immunotherapy, which are seen as the new generation of cancer treatment

Successful Kosher Food & Wine Experience in US, Europe and Israel

The 9th annual Kosher Food and Wine Experience sponsored by Kedem (Royal Wine Corporation)takes place this evening at the Metropolitan Pavilion in Manhattan. More than 1,000 bottles of wines and spirits from the US, France , Israel, and other fine wine regions around the world will be sampled. Initially held only in New York, the event has expanded to such cities as Miami, Paris, Tel Aviv and London. Nathan Herzog, the Executive Vice President for Royal Wines says that “ each event has its own flavor and we always make sure to get kosher winemakers from all over the globe so people can talk directly with them”. He adds “it’s the best vehicle to get the message directly to the consumers of the great kosher wines available today”. The KFWE in New York is divided into two parts, the first for trade and professionals and the second for some 1800 food connoisseurs who in addition to the wines can taste great foods from some of the New York region’s finest restaurants and caterers. Last week, more than 800 people attended a similar event in London. Wines from Israel are very much in demand - there is a lot of interest, many new wines and vintages, and a lot of growth and movement, states Jay Buchsbaum, VP marketing and Director of Wine Education, the Royal Wine Corporation /Kedem. “The single strongest growth area in the kosher wine world is Israel, hands down. We almost can’t bring it in fast enough and some of the wineries can’t produce enough volume to satisfy the U.S demand”. To date Royal Wine offers more than 20 different Israeli wineries in its portfolio. Kosher wine in America is big business – upwards of $28 million in sales, according to estimates made several years ago. kosher Today

Successful Kosher Food & Wine Experience in US, Europe, and Israel "Getting the Message Out" Says Kedem The 9th annual Kosher Food and Wine Experience sponsored by Kedem (Royal Wine Corporation)takes place this evening at the Metropolitan Pavilion in Manhattan. More than 1,000 bottles of wines and spirits from the US, France , Israel, and other fine wine regions around the world will be sampled. Initially held only in New York, the event has expanded to such cities as Miami, Paris, Tel Aviv and London. Nathan Herzog, the Executive Vice President for Royal Wines says that “ each event has its own flavor and we always make sure to get kosher winemakers from all over the globe so people can talk directly with them”. He adds “it’s the best vehicle to get the message directly to the consumers of the great kosher wines available today”. The KFWE in New York is divided into two parts, the first for trade and professionals and the second for some 1800 food connoisseurs who in addition to the wines can taste great foods from some of the New York region’s finest restaurants and caterers. Last week, more than 800 people attended a similar event in London. Wines from Israel are very much in demand - there is a lot of interest, many new wines and vintages, and a lot of growth and movement, states Jay Buchsbaum, VP marketing and Director of Wine Education, the Royal Wine Corporation /Kedem. “The single strongest growth area in the kosher wine world is Israel, hands down. We almost can’t bring it in fast enough and some of the wineries can’t produce enough volume to satisfy the U.S demand”. To date Royal Wine offers more than 20 different Israeli wineries in its portfolio. Kosher wine in America is big business – upwards of $28 million in sales, according to estimates made several years ago. kosher Today

New Jersey Rabbi develops app to support Israeli products

A free application for those who want to support Israel by helping Israeli made products is now downloadable for all major smart phones. The new app, Am Yisrael Buy was created by Rabbi Daniel M. Cohen, spiritual leader of Temple Sharey Tefilo- – Israel in South Orange New Jersey. “There is an international movement called BDS – Boycott, Divestment and Sanctions – aimed at boycotting Israel and its products” said Cohen. “The movement demonizes Israel and has, as some of its leading proponents, anti—Semites whose ultimate goal is the destruction of the State of Israel. When I learned there are BDS apps that make it easier to boycott Israeli products and goods and spread their hatred, and then found there was no commensurate Pro – Israel app, I just had to act. That was the impetus for creating Am Yisrael Buy.” Initially Rabbi Cohen turned to some of his colleagues in the rabbinic community to see if they would join him in helping to promote an app for Israel. Once they agreed, he contacted a developer to help him create the app. The developer had some good ideas but was moving too slowly, so Rabbi Cohen decided to create it himself using a template – driven app development software tool. He taught himself to use the interface and Am Yisrael Buy was born. The app offers a list of Israeli made products, and where to buy them, as well as additional ways to support Israel. “As I was putting together the list I realized there were other ways to support Israel, so I added a section with some of the media outlets that cover Israel, outlets that help expose media bias against Israel, and included a number of ways people can donate to Pro – Israel organizations.” Added Cohen Jewish Advocate 10/10/14

Online Gift Stores Fight Boycott of Israel

With the continued growth of online shopping, Israeli online gift stores are spending more and promoting their products abroad in an effort to encourage Jews and non-Jews around the world to support Israel's economy - and challenge the BDS campaign against Israel. They are marking their products with "Made in Israel" in a clear sign for buyers to know of the Israeli designers. While much of the cheaper products are manufactured in China, many of the fine arts and crafts are produced in Israel. IsraelGiftStore - Shop Now The BDS boycott, divesture and sanctions campaign waged against Israel has steadily advanced around the world. However, in the past 3 years, Israel's Central Bureau of Statistics reports there has been an increase in exports each year between 3-6%. This is good news for the online stores which are targeting new markets. The focus of these Israeli web stores has been moving to markets beyond the Jewish community including the Christian supporters, and countries in Latin America and Asia which have strong economies. For these, the emphasis tends to be more with products from the Holy land, but not necessarily religious items. Many Jewish and Christian organizations and individuals are vocally advocating for Israel, but most still shop in their local communities (where much is imported from Asia) or online for the best price. The online stores are suggesting that the priority should be "buying blue and white". One such company, www.IsraelGiftStore.com carries only products that are designed and manufactured in Israel, including the packaging. It brands its products as higher quality with lower margins and quick service to encourage the online shopping experience. IsraelGiftStore - Shop Now "We started the Israel Gift Store after seeing the force of the BDS campaign and the growing divestures of companies doing business with Israel. We felt we needed to take a proactive stance to show the amazing creativity, diversity and culture of our country. We do this through beautiful products, and through our promotions," said Tali Omer, founder of the Israel Gift Store. "It's a whole new ballgame with the social media promotions, and not any less expensive than operating a physical store. But the rewards for promoting Israel abroad are so much greater," Tali explains. The international reach of the online stores has the added advantage of fewer peaks and valleys in sales. Holidays and special events in other countries and cultures occur regularly, to create a more even ordering for manufacturers. With the statistics proving positive, the advantages of the online gift stores work both for the economy, the producers and the consumers. Thank you! We appreciate your business and your support of Israel. Tali Omer Israel Gift Store

Christians United For Israel

ornament 2014 Dear Friend , Christians United for Israel (CUFI) is the largest pro-Israel organization in the United States with over one million members and one of the leading Christian grassroots movements in the world. We have only 25 staff, but serve over one million members and conduct over 40 pro-Israel events every month. Statement of Purpose The purpose of Christians United For Israel (CUFI) is to provide a national association through which every pro-Israel church, parachurch organization, ministry or individual in America can speak and act with one voice in support of Israel in matters related to Biblical issues. BDS (Boycott, Divestment and Sanctions) is the latest effort to attack the Jewish people and delegitimize the Jewish State. The people promoting BDS are Israel haters who are trying to treat Israel like apartheid South Africa. They're hoping you'll forget that Israel is one of the most racially diverse countries in the world. They're hoping you'll not know that the freest Arabs in the Middle East are the Arab citizens of the Jewish State of Israel. They're hoping you won't see in their boycott of Jewish products and scholars a parallel to the Nazi boycott of Jewish merchants and academics decades ago. We are pushing back against the boycott of Israeli goods by purchasing Israeli goods. That's why our CUFI Christmas ornament is made in Israel! For your gift of $20 or more you receive a silver made in Israel CUFI Christmas Ornament. Or for your gift of $35 or more you will receive both the silver and gold made in Israel CUFI Christmas ornaments. May God Bless You and Those that You Love, Pastor John Hagee David Brog Chairman Executive Director Stand with Israel - Donate now! info@cufi.org

Friends of Israel

Monna Young Nov 11th, 2:14pm If you've never heard of us before: Hello from Sussex Friends of Israel! We are a group who have just started up in response to intense and aggressive demonstrations in our town, by the Boycott Divestment and Sanctions movement outside shops that sell Israeli produce. Upset and disturbed by weekly harassment, chanting and shouting of lies and hatred by these activists outside these shops, members of the Jewish and Christian community of Brighton began a counter-protest, forming the group which is now known as Sussex Friends of Israel. We've just passed our second anniversary since we first started counter-protesting against the BDS, giving out pro-Israel leaflets, holding our own rallies, talking and engaging the public and giving them another narrative and another side to the story. Members from all religions and backgrounds have thanked us for being a presence in Brighton, UK,, not only because they have also experienced harassment by the BDS and other groups, but because they feel marginalised and threatened by such a divisive, loud and aggressive movement on their streets. Would you visit and Like (or/and Share?) our page and thus support our small but ever growing online community which aims to promote and share the truth about Israel and the wider Jewish Community? Here is Sussex Friends of Israel’s link! https://www.facebook.com/pages/Sussex-Friends-Of-Israel/521248807933259?fref=ts


https://www.youtube.com/watch?v=5muyjf1mlOk highlight the above link to open. very interesting video

How Can You Help Israel?

During these difficult times, when we can give less to help others, the Israeli organizations that rely on U.S. donations are struggling like never before. The drop in the value of the U.S. dollar means charitable donations buy far less than in the recent past. And with food prices soaring worldwide, the numbers of truly poor, keep rising. The ripple effect from the U.S. financial crisis is devastating to charities and businesses in Israel. Israel's economy has recovered admirably, but there is still suffering and crushing poverty in much of the country. Self defense is expensive. Rebuilding war-ravaged lives, homes and businesses requires support. Most social services have been reduced drastically. Over 1.6 million people in Israel live below the poverty line. One in every three Israeli children is growing up poor- without enough food, without dental care, or shoes that fit. This store is our small attempt to make a difference. Our goal is to make high quality Israeli products easier to find and purchase for U.S. consumers. We urge our customers to support both America and Israel by purchasing MADE IN U.S.A. and MADE IN ISRAEL products whenever possible. Conscious spending for everyday needs in this way helps good people keep their jobs. It is a simple way to help counter the economic damage done by terrorists. Our warehouse is in Baltimore, so you wont have to wait weeks or pay exhorbitant shipping rates to buy MADE IN ISRAEL items. Please browse through our wonderful selection of THOUSANDS of useful, affordable and beautiful items, with favorite brands like Ahava, Dr. Fischer, Elite, Osem, Halutza, Neca 7, Ayala Bar, Yair Emanuel, Natural Formula, Safed Candles, and with hard-to-find items from small manufacturers and artists too. 100% of net profits from our internet sales are donated to Israeli charities. Israelproducts.com


Malka Beer has become the first brand of Israeli craft beer to become available in the United States, and Illinois is now one of the first US markets to support it, distributed by Chicago owned and operated Louis Glunz Beer and imported by Sublime Imports. Located in the upper Galilee town of Yehiam (pronounced YEH-HEE-YAHM), at the foot of the 12th century Montfort Castle, Malka is one of the first micro-breweries in Israel. Malka maintains a tradition of hand-crafting small batches of beer, specializing in traditional Belgian, German, and English styles while imparting a local Israeli twist-using natural water from the Ga�aton Springs and local flavors. You can discover more about Malka Beer via their website: http://malkabeer.co.il/en/ Questions about where to find Malka Beer can be directed to your favorite local craft beer retailer and/or their distributor: Louis Glunz Beer via phone or email: (847) 676-9500 and info@glunzbeers.com

American Business Thrives in Israel

Amazon announced during a visit to Israel in October ,"We are setting up in Israel to support our cloud activity". Amazon's service and sales center, to open in 2014, will also service the Middle East and Africa. General Motors' Israel R&D facility is working on a self driving, self parking car that decreases the number of auto accidents. Asurion Corporation, a provider of technical support to the wireless phone industry, brought Israeli high-tech startup Soluto for$130 million. (Assaf Glad, Al-Monitor; David Shamah, Times of Israel; Orr Hirschauge, Ha'aretz)


Inspiro Medical’s Inspiromatic, invented by the father of a child with asthma, passed a critical clinical study and now seeks partners for development. A smart dry-powder inhaler for children, developed by Israeli mechanical engineer Nimrod Kaufmann with Dr. Guy Steuer, senior pulmonologist at Schneider Children’s Medical Center in Petah Tikvah, just completed a successful clinical trial at Schneider. The Inspiromatic device. Inspiromatic is produced by Inspiro Medical, a portfolio company of The Trendlines Group, and is meant to take the place of hard-to-use nebulizers for young children as well as the elderly and people with certain disabilities. Kaufmann, who came from a background in medical devices research and development, knew that dry-powder inhalers do a better, faster job with less risk of error and contamination, but kids in particular can’t use them properly. Inspiromatic has an internal microcontroller and flow sensor that detects the right time to deliver the medication and automatically disperse the drug particles in the right size without need for forceful inhalation. The randomized, crossover, double-blind study aimed to objectively assess the efficacy and safety of Inspiromatic in delivering bronchodilator meds to 30 children with asthma, aged 8-18, compared to a competitive inhaler already on the market. According to a company statement, the results demonstrated superior results for the Inspiromatic, even in patients with poor inhalation technique, and it was highly rated by patients for ease of use. “This successful study will enable us to move to the next step in the company development and partner with pharmaceutical companies to develop drug-device combinations and also bring better therapy to patients with poor inhalation technique,” said Kaufmann. By: Abigail Klein Leichman 6-10-13


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